Charles J Ryan Selected Research

Fatigue

1/2023	Rucaparib or Physician's Choice in Metastatic Prostate Cancer.
1/2018	A Phase II Trial of Selinexor, an Oral Selective Inhibitor of Nuclear Export Compound, in Abiraterone- and/or Enzalutamide-Refractory Metastatic Castration-Resistant Prostate Cancer.
12/2007	Phase II study of ketoconazole plus granulocyte-macrophage colony-stimulating factor for prostate cancer: effect of extent of disease on outcome.

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Charles J Ryan Research Topics

Disease

163	Prostatic Neoplasms (Prostate Cancer) 01/2024 - 12/2003
49	Neoplasms (Cancer) 04/2024 - 05/2004
26	Neoplasm Metastasis (Metastasis) 01/2024 - 11/2005
23	Disease Progression 01/2023 - 11/2005
8	Pain (Aches) 01/2023 - 08/2013
7	Circulating Neoplastic Cells 11/2018 - 03/2010
5	Hypertension (High Blood Pressure) 01/2024 - 03/2010
3	Fatigue 01/2023 - 12/2007
3	Neutropenia 01/2022 - 06/2009
2	Carcinogenesis 08/2023 - 01/2018
2	Nausea 01/2023 - 01/2018
2	Febrile Neutropenia 01/2022 - 01/2019
2	Cognitive Dysfunction 01/2022 - 01/2018
2	Heart Diseases (Heart Disease) 11/2015 - 02/2015
2	Cancer Pain 10/2015 - 01/2013
2	Renal Cell Carcinoma (Grawitz Tumor) 02/2015 - 09/2011
2	Hypokalemia 05/2011 - 03/2010
2	Leukemia 04/2007 - 05/2006
1	Squamous Cell Carcinoma (Epidermoid Carcinoma) 08/2023
1	Dysuria 01/2023
1	Urinary Retention 01/2023

Drug/Important Bio-Agent (IBA)

54	AndrogensIBA 01/2024 - 12/2003
31	Abiraterone AcetateIBA 01/2018 - 03/2010
30	Prednisone (Sone)FDA LinkGeneric 01/2022 - 03/2007
27	Hormones (Hormone)IBA 01/2023 - 05/2005
25	Prostate-Specific Antigen (Semenogelase)IBA 01/2023 - 05/2004
25	Docetaxel (Taxotere)FDA Link 01/2023 - 05/2005
25	Androgen Receptors (Androgen Receptor)IBA 01/2023 - 04/2007
16	abirateroneIBA 01/2023 - 05/2011
14	Biomarkers (Surrogate Marker)IBA 08/2023 - 01/2013
12	Testosterone (Sustanon)FDA Link 02/2019 - 09/2007
8	AntigensIBA 11/2022 - 01/2009
7	enzalutamideIBA 01/2022 - 02/2015
5	rucaparibIBA 01/2023 - 01/2020
5	Poly(ADP-ribose) Polymerase InhibitorsIBA 12/2021 - 01/2016
5	Ketoconazole (Nizoral)FDA LinkGeneric 04/2018 - 04/2007
5	Mitoxantrone (Novantrone)FDA LinkGeneric 01/2017 - 11/2005
5	Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF)IBA 11/2016 - 12/2007
5	Insulin-Like PeptidesIBA 07/2013 - 03/2007
3	apalutamideIBA 01/2024 - 12/2016
3	Dihydrotestosterone (Androstanolone)IBA 04/2018 - 08/2008
3	Insulin (Novolin)FDA Link 01/2018 - 03/2007
3	Opiate AlkaloidsIBA 01/2018 - 01/2013
3	gallium 68 PSMA-11IBA 01/2018 - 01/2017
3	Adrenal Cortex Hormones (Corticosteroids)IBA 01/2016 - 05/2015
3	SteroidsIBA 05/2015 - 05/2014
3	Tyrosine Kinase InhibitorsIBA 02/2015 - 09/2009
3	IGF Type 1 Receptor (IGF 1 Receptor)IBA 07/2012 - 03/2007
2	antiarrhythmic peptide (AAP)IBA 01/2024 - 07/2017
2	CytokinesIBA 12/2023 - 12/2007
2	MyokinesIBA 12/2023 - 01/2022
2	RNA (Ribonucleic Acid)IBA 08/2023 - 01/2022
2	DNA (Deoxyribonucleic Acid)IBA 08/2023 - 01/2016
2	Proteins (Proteins, Gene)FDA Link 01/2023 - 09/2020
2	Poly(ADP-ribose) Polymerases (Poly ADP Ribose Polymerase)IBA 01/2023 - 11/2018
2	LigandsIBA 01/2022 - 03/2010
2	Steroid Synthesis InhibitorsIBA 01/2020 - 12/2014
2	Radium-223IBA 01/2019 - 10/2014
2	Cell-Free Nucleic AcidsIBA 11/2018 - 01/2017
2	Gonadotropin-Releasing Hormone (GnRH)FDA Link 01/2018 - 05/2009
2	Dehydroepiandrosterone (DHEA)IBA 12/2017 - 10/2009
2	Angiogenesis InhibitorsIBA 04/2017 - 05/2006
2	pazopanib FDA Link 04/2017 - 02/2015
2	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 04/2017 - 03/2006
2	Phosphotransferases (Kinase)IBA 01/2017 - 08/2008
2	IpilimumabIBA 09/2015 - 01/2009
2	Somatostatin (Somatotropin Release-Inhibiting Factor)IBA 06/2015 - 07/2012
2	Masoprocol (Actinex)FDA Link 01/2012 - 08/2008
2	CilengitideIBA 12/2011 - 03/2006
2	IntegrinsIBA 12/2011 - 03/2006
2	pegfilgrastim (Neulasta)FDA Link 06/2011 - 06/2009
2	ixabepilone (BMS 247550)FDA Link 06/2011 - 06/2009
2	MineralocorticoidsIBA 05/2011 - 03/2010
2	Steroid 17-alpha-Hydroxylase (17 alpha Hydroxylase)IBA 03/2010 - 03/2010
2	Androgen Antagonists (Antiandrogens)IBA 05/2009 - 04/2007
2	Protein-Tyrosine Kinases (Tyrosine Kinase)IBA 02/2008 - 10/2007
2	Estramustine FDA Link 06/2007 - 07/2004
2	Imatinib Mesylate (Gleevec)FDA Link 06/2007 - 10/2006
1	Phosphates (Orthophosphate)IBA 04/2024
1	PentosesIBA 04/2024
1	Fatty Acids (Saturated Fatty Acids)IBA 04/2024
1	Immune Checkpoint InhibitorsIBA 08/2023
1	A-Form DNA (A-DNA)IBA 01/2023
1	darolutamideIBA 01/2023
1	insulin receptor-related receptor (IRR)IBA 01/2023
1	Opioid Analgesics (Opioids)IBA 01/2023
1	pembrolizumabIBA 01/2022
1	COVID-19 VaccinesIBA 01/2022
1	Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA 01/2022
1	Metformin (Glucophage)FDA LinkGeneric 01/2022
1	Filgrastim (Neupogen)FDA Link 01/2022
1	E2F1 Transcription FactorIBA 01/2022

Therapy/Procedure

105	Castration 01/2024 - 10/2007
78	Therapeutics 08/2023 - 12/2003
34	Drug Therapy (Chemotherapy) 01/2023 - 11/2002
8	Aftercare (After-Treatment) 01/2023 - 06/2015
7	Immunotherapy 04/2024 - 12/2007
6	Radiotherapy 01/2022 - 05/2004
3	Prostatectomy (Retropubic Prostatectomy) 01/2024 - 10/2006
2	Life Support Care 10/2015 - 11/2014